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随着抗生素耐药性问题日趋严重,天然化合物的抗菌作用成为近年来的研究热点,多种黄酮类化合物都表现出较好的抗菌活性,并且与抗生素有良好的协同作用。本文对黄酮类化合物的来源、抑菌方法、抑菌范围以及应用前景做了概述,旨在为系统研究黄酮化合物抑菌作用提供依据。
Abstract：As the problem of antibiotics resistance is becoming more and more serious,the antibacterial effect of the natural compound,has become a hotspot in recent years.Various flavonoids have shown good antibacterial activity and have good synergistic effect with antibiotics.In this paper,the sources,bacteriostatic method,bacteriostatic range and application prospect of flavonoids were summarized in order to provide the basis for the systematic study of the bacteriostatic effects of flavonoids.
[1]唐毓,李丽,周平和,等.天然植物中黄酮类化合物的研究进展[J].现代畜牧兽医,2016(5):45-50.
[2]张锡彬.红薯茎叶多糖和黄酮提取物的抗菌及降血糖功能研究[D].大连工业大学,2008.
[3]Grange J M,Davey R W.Antibacterial properties of propolis(bee glue)[J].Journal of the Royal Society of Medicine,1990,83(3):159.
[4]王茹,谢印乾,沈志强,等.蜂胶的免疫增强作用及其在疫苗中的应用[J].中国畜牧兽医,2007,34(2):14-16.
[5]崔莉,孙娥,陈玲玲,等.生物转化在黄酮类化合物中的研究与应用[J].中华中医药杂志,2013(3):764-767.
[6]孙阿宁,任改艳,邓超,等.牡荆素减轻小鼠溃疡性结肠炎的药效作用及机制研究[J].中国药理学通报,2014,v.30(12):1677-1681.
[7]Siah M,Farzaei M H,Ashrafi-Kooshk M R,et al.Inhibition of guinea pig aldehyde oxidase activity by different flavonoid compounds:An in vitro study[J].Bioorganic Chemistry,2016(64):74-84.
[8]朱宇旌,李艳,于治姣,等.酸模叶蓼类黄酮对小鼠生长、免疫和抗氧化性能的影响[J].现代畜牧兽医,2015(2):1-7.
[9]Harborne J B,Baxter H.The handbook of natural flavonoids.Volume 1 and volume 2[J].Handbook of Natural Flavonoids,1999.
[10]王哲元,张璐,张有成.天然黄酮类化合物抗肿瘤作用机制的研究[J].西部中医药,2018(5).
[11]张庆建,赵毅民,杨明,等.黄酮类化合物对中枢神经系统的作用[J].中国中药杂志,2001,26(8):511-514.
[12]Yao Z,Li Z,Ji G.Efficacy of polyphenolic ingredients of chinese herbs in treating dyslipidemia of metabolic syndromes[J].Journal of Integrative Medicine,2014,12(3):135-146.
[13]Zhu H,Zhang Y,Ye G,et al.In vivo and in vitro antiviral activities of calycosin-7-o-beta-d-glucopyranoside against coxsackie virus b3[J].Biological&Pharmaceutical Bulletin,2009,32(1):68-73.
[14]方一杰,徐岩成,安毛毛,等.黄酮类化合物的药动学和药理作用研究进展[J].药学服务与研究,2015,15(1):6-9.
[15]Qiu J,Jiang Y,Xia L,et al.Subinhibitory concentrations of licochalcone a decrease alpha-toxin production in both methicillin-sensitive and methicillin-resistant staphylococcus aureus isolates[J].Letters in Applied Microbiology,2010,50(2):223-229.
[16]Uzel A,Sorkun K,On?a?O,et al.Chemical compositions and antimicrobial activities of four different anatolian propolis samples[J].Microbiological Research,2005,160(2):189-195.
[17]Tereschuk M L,Riera M V,Castro G R,et al.Antimicrobial activity of?avonoids from leaves of tagetes minuta[J].Journal of Ethnopharmacology,1997,56(3):227-232.
[18]Rukayadi Y,Lee K,Han S,et al.In vitro activities of panduratin a against clinical staphylococcus strains[J].Antimicrobial Agents&Chemotherapy,2009,53(10):4529-4532.
[19]Mbaveng A T,Ngameni B,Kuete V,et al.Antimicrobial activity of the crude extracts and five flavonoids from the twigs of dorstenia barteri(moraceae)[J].Journal of Ethnopharmacology,2008,116(3):483-489.
[20]Kuete V,Simo I K,Ngameni B,et al.Antimicrobial activity of the methanolic extract,fractions and four?avonoids from the twigs of dorstenia angusticornis engl.(moraceae)[J].Journal of Ethnopharmacology,2007,112(2):271-277.
[21]Oz?elik B,Orhan I,Toker G.Antiviral and antimicrobial assessment of some selected flavonoids[J].Zeitschrift Fur Naturforschung C A Journal of Biosciences,2006,61(10):632-638.
[22]Otsuka N,Liu M H,Shiota S,et al.Anti-methicillin resistant staphylococcus aureus(mrsa)compounds isolated from laurus nobilis[J].Biological&Pharmaceutical Bulletin,2008,31(9):1794-1797.
[23]Radwan M M,Rodriguezguzman R,Manly S P,et al.Sepicanin a-a new geranyl flavanone from artocarpus sepicanus with activity against methicillin-resistant staphylococcus aureus(mrsa)[J].Phytochemistry Letters,2009,2(4):141-143.
[24]Sato M,Tanaka H,Tani N,et al.Different antibacterial actions of isoflavones isolated from erythrina poeppigiana against methicillin-resistant staphylococcus aureus[J].Letters in Applied Microbiology,2010,43(3):243-248.
[25]Basile A,Conte B,Rigano D,et al.Antibacterial and antifungal properties of acetonic extract of feijoa sellowiana fruits and its effect on helicobacter pylori growth[J].Journal of Medicinal Food,2010,13(1):189.
[26]?mejkal,KarelChudík,ˇEk S K,et al.Antibacterial c-geranyl?avonoids from paulownia tomentosa fruits[J].2008.
[27]Qiu J,Jiang Y,Xia L,et al.Subinhibitory concentrations of licochalcone a decrease alpha-toxin production in both methicillin-sensitive and methicillin-resistant staphylococcus aureus isolates[J].Letters in Applied Microbiology,2010,50(2):223-229.
[28]A U,K S,O O,et al.Chemical compositions and antimicrobial activities of four different anatolian propolis samples[J].Microbiological Research,2005,160(2):189-195.
[29]Singh G,Kumar P.Phytochemical study and screening for antimicrobial activity of flavonoids of euphorbia hirta[J].International Journal of Applied&Basic Medical Research,2013,3(2):111-116.
[30]Cushnie T P T,Lamb A J.Recent advances in understanding the antibacterial properties of flavonoids[J].International Journal of Antimicrobial Agents,2011,38(2):99-107.
[31]Cushnie T P T,Lamb A J.Detection of galangin-induced cytoplasmic membrane damage in Staphylococcus aureus by measuring potassium loss[J].Journal of Ethnopharmacology,2005,101(1-3):243-248.
[32]Gradi?ar H,Pristov?ek P,Plaper A,et al.Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site[J].Journal of medicinal chemistry,2007,50(2):264-271.
[33]Navarro-Martinez M D,Navarro-Peran E,Cabezas-Herrera J,et al.Antifolate activity of epigallocatechin gallate against stenotrophomonas maltophilia[J].Antimicrobial Agents and Chemotherapy,2005,49(7):2914-2920.
[34]Chinnam N,Dadi P K,Sabri S A,et al.Dietary bioflavonoids inhibit Escherichia coli ATP synthase in a differential manner[J].International Journal of Biological Macromolecules,2010,46(5):0-486.
[35]Wu D,Kong Y,Han C,et al.d-Alanine:d-alanine ligase as a new target for the flavonoids quercetin and apigenin[J].International Journal of Antimicrobial Agents,2008,32(5):421-426.
[36]Jeong K W,Lee J Y,Kang D I,et al.Screening of?avonoids as candidate antibiotics against\r,enterococcus faecalis[J].Journal of Natural Products,2009,72(4):719-724.
[37]Kuete V,Simo I K,Ngameni B,et al.Antimicrobial activity of the methanolic extract,fractions and four?avonoids from the twigs of dorstenia angusticornis engl.(moraceae)[J].Journal of Ethnopharmacology,2007,112(2):271-277.
[38]陈学红,孙会刚,唐仕荣,等.绿芦笋皮黄酮的抑菌性能研究[J].农业机械,2011(14):170-172.
[39]杨辑,董洁娴,赵晟楠.薇菜异黄酮的微波辅助提取及其抑菌性研究[J].食品工业,2014(1):105-108.
[40]黄晓昆,黄晓冬.赤楠叶黄酮类化合物的提取及其体外抗菌活性研究[J].安徽农业科学,2008,36(13):5257-5258.
[41]R?Os J L,Recio M C.Medicinal plants and antimicrobial activity[J].Journal of Ethnopharmacology,2005,100(1):80-84.
[42]Harborne J B.The?avonoids:Advances in research since 1980[M].London:Chapman Hall Press,1988。
[43]赖毅勤,周宏兵.近年来黄酮类化合物提取和分离方法研究进展[J].食品与药品,2007,9(4):54-58.
[44]Dasgupta N,Ranjan S,Saha P,et al.Antibacterial activity of leaf extract of mexican marigold(Tagetes erecta)against different gram positive and gram negative bacterial strains[J].Journal of Pharmacy Research,2012,5(8):4201-4203.
[45]Verma P,Verma A.Evaluation of antibacterial activity of different parts of Tagetes erecta[J].International Journal of Pharmacy&Life Sciences,2012.
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中图分类号:TQ464
引用信息:
[1]钟宜科,吴迪,花晓丹,等.黄酮类化合物抑菌作用研究进展[J].中国食品添加剂,2019,30(08):166-171.
2019-06-24
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